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8 Biopharma Trends and Top Startups to Follow in 2017

   by Andrii Buvailo    7408

Pharmaceutical industry is rapidly evolving, influenced by emerging novel technologies and recent advances in Life Sciences and Big Data analysis, new government policies and regulations, and a changing market conjuncture.

Let’s review some of the most powerful trends that will dominate the industry in 2017 and promising biopharmaceutical startups riding their waves.

The Power Of Machine Learning For Drug Discovery

   by Andrii Buvailo    4009

An IBM’s executive Deborah DiSanzo just announced a collaboration with a pharmaceutical giant Pfizer to speed up anticancer drug discovery. This is yet another sign of a technological transformation unfolding in biopharmaceutical industry.

The newly formed partnership will bring the power of IBM’s supercomputer Watson and its artificial intelligence system to help researchers at Pfizer advance “immuno-oncology”, a potentially promising area for cancer research.

A Drug Repurposing Case By Biotech Startup Forty Seven Inc

   by Andrii Buvailo    2238

Drug repositioning is a smart and cost-effective approach used by some pharmaceutical companies to re-invent their previously successful drugs in a new role and generate extra value from existing assets.   

Pharmaceutical companies find drug repurposing programs largely beneficial over usual drug development from scratch. because they allow saving money on R&D, toxicity tests and other different trials already conducted with a known drug. The risks of failure at a later stage of repurposed drug development are lower, therefore the whole project becomes more attractive from the investor’s point of view.

A Second Chance for Integrins: Biotech Startup Morphic Therapeutic Reinvents Old Target

   by Andrii Buvailo    1324

Integrins are a group of transmembrane receptors playing a major role in cell-cell and cell-extracellular matrix (ECM) interactions. When triggered, integrin receptors transduce signals to the interior of the cell, providing quick and flexible “status update” about chemical composition and mechanical status of the ECM. It results in a cellular response, such as a change in the cell shape, regulation of the cell cycle, adjusting motility, or adding new receptors to the cell membrane.