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Covering emerging technologies, innovations, and companies

New Tools, Products And Technologies

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11 Startups Using Quantum Theory To Accelerate Drug Discovery

   by Andrii Buvailo    2352
11 Startups Using Quantum Theory To Accelerate Drug Discovery

Molecular mechanics (MM) is a traditional computational approach when it comes to modeling in synthetic organic chemistry, medicinal chemistry and versatile aspects of drug design. However, MM methods have significant limitations, for example, when used to study electron-based properties within the drug-receptor microenvironment. Quantum mechanical (QM) methods allow to substantially increase the accuracy of predictions and provide much more relevant models of chemical and biological objects and their interactions, but QM methods are extremely (often prohibitively) computationally costly.

However, a series of advancements over recent years allowed to expand horizons in this direction, for example, the emergence of density functional theory (DFT), the overall increase in the computation power and the emergence of distributed cloud-based computational infrastructures.

Introducing Sysrev: The Intelligent Platform For Document Review And Automated Data Extraction

   by Thomas Luechtefeld    452
Introducing Sysrev: The Intelligent Platform For Document Review And Automated Data Extraction

In today’s technological world, data is perhaps the single most important driver of a business’ success. Access to relevant data allows businesses to make a variety of informed decisions. Unfortunately, acquiring this data can be quite cumbersome as employees spend countless hours manually reviewing documents. This is especially true for more complex reviews such as journal publications, patient records, or technical specifications. Sysrev offers enterprise a platform for managing collaborative document reviews, injecting machine learning into the review process to increase accuracy and efficiency. Depending on the data source and task, Sysrev can even automate data extraction.

Sysrev, launched in June 2019, is an intelligent platform for document reviews and automated data extraction. Sysrev optimizes the review process with machine learning and adds efficiency through its intuitive, and collaborative, interface.

Chemchart Enterprise: an Intelligent Platform for Chemical Data Management

   by TJ Bozada    439
Chemchart Enterprise: an Intelligent Platform for Chemical Data Management

Chemical data management is an important process to a number of industries, especially those engaged in manufacturing or research and development.  Unfortunately, chemical data is as unwieldy to manage as it is important.  This is for a variety of reasons, but the biggest contributing factor is the sheer amount of data available to the public and managed by an enterprise.  For decades, chemical data has been recorded in paper, and then excel sheets, and now databases.  While efforts have been made to homogenize, or at least centralize this data, there is not one single solution for indexing and searching the wide variety of data types, and sources, managed by an individual enterprise.  Chemchart Enterprise changes this paradigm by combining the flexibility of big data with the precision of machine learning, providing a single solution for managing the entire organization chemical space.

Pharma Companies Join Forces to Train AI for Drug Discovery Using Blockchain

   by Andrii Buvailo    2616
Pharma Companies Join Forces to Train AI for Drug Discovery Using Blockchain

The newly organized research project “MELLODDY” (Machine Learning Ledger Orchestration for Drug Discovery), involving ten large pharma companies and seven technology providers, is that kind of deals which can catalyze a transition of the pharmaceutical industry to a new level -- a “paradigm shift”, as one might refer to it in terms of Thomas Kuhn’s “The Structure of Scientific Revolutions”.

The project aims at developing a state-of-the-art platform for collaboration, based on Owkin’s blockchain architecture technology, which would allow collective training of artificial intelligence (AI) algorithms using data from multiple direct pharmaceutical competitors, without exposing their internal know-hows and compromising their intellectual property -- for the collective benefit of everyone involved. 

Genetic Test for Antimicrobial Resistance

   by Tim Sandle    560
Genetic Test for Antimicrobial Resistance

Scientists have put together a sensitive method to determine if bacteria carry a gene that can cause resistance to two common antibiotics. The test is rapid and has been tested against the bacterium which causes ‘strep throat’ and other respiratory illnesses.