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Navigating In REAL Chemical Space To Find Novel Medicines (Now 3.8 Billion Molecules)

   by Andrii Buvailo    1506
Navigating In REAL Chemical Space To Find Novel Medicines (Now 3.8 Billion Molecules)

[Latest update: 27.07.2018]

February 6 2018 will be marked in history as the day when an automobile embarked on a million year trip into far space. On that day, Falcon Heavy, the 230ft megarocket, successfully launched from Cape Canaveral, Florida, bringing on board Elon Musk’s personal Tesla Roadster with a crash test dummy called 'Starman' strapped into the driver's seat.

"The imagery of it is something that's going to get people excited around the world." says Elon Musk, a guy who literally revolutionized the area of space travel having developed and successfully tested first reusable rockets in the aerospace history, opening new horizons for cosmos explorations.

While advances in aeronautics are making news headlines daily, a much quieter scientific revolution is also happening in the area of “chemical space” explorations -- the one which might soon uncover novel medicines to cure diseases.

36 Web Resources For Target Hunting In Drug Discovery

   by Alfred Ajami, Andrii Buvailo    5686

Choosing the right biological target or a combination of targets is a fundamental task for any successful drug discovery project. All the subsequent efforts -- be it a small molecule hit identification, lead optimization, pharmacokinetic studies, or a clinical trial -- will just be as effective, at the end of the day, as was the initial decision to choose one target or another.

Takeda Partners With Numerate To Use Artificial Intelligence For Drug Discovery

   by BiopharmaTrend    5275

A multi-year research agreement has just been announced between Takeda Pharmaceuticals (TSE: 4502) and an Artificial Intelligence (AI)-driven computational drug design company Numerate, Inc. Under this contract, Numerate will have to come up with new clinical candidates in the Takeda’s core therapeutic areas: oncology, gastroenterology, and central nervous system disorders.

Chinese Biotech Innovent Biologics, Inc. Raises USD 260M To Accelerate Biologics Development

   by Andrii Buvailo    3535

Chinese biopharmaceutical industry investment landscape has been marked by a new record -- USD $260M Series D investment raised by Innovent Biologics, Inc. exceeded China's previous investment deals for biopharmaceutical industry and became one of the largest biopharmaceutical industry fundraising events in the world for both private and public financing markets in 2016.

Copenhagen-based Biotech Pcovery To Extend Collaboration With Enamine

   by Andrii Buvailo    2269

Founded in 2009, Pcovery is a Danish biotech startup company involved in drug discovery to fight invasive fungal infections. On November 22, 2016 Pcovery announced the extension of collaboration with a leading producer of building blocks and screening libraries -- Enamine Ltd. In the ongoing drug discovery program, Pcovery will utilize Enamine’s experience in synthesis of small compound libraries and singletons, route scouting, process optimization, and scale-up of lead compounds.