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Interviews

Section: Biopharma Insights     View all sections


[Interview] Demystifying the Role of Artificial Intelligence in The Life Sciences

   by Andrii Buvailo    290
[Interview]  Demystifying the Role of Artificial Intelligence in The Life Sciences

In this interview, Rasim Shah, Director at OKRA Technologies provided a glimpse into how the company applies state of the art machine learning technologies to solve real world challanges in the life sciences. Rasim also agreed to answer several questions about a more general context of AI in pharma, its current challanges and future perspective, as well as describe the current efforts the European Union puts into supporting the AI ecosystem in the region.

 

Rasim Shah, Director at OKRA Technologies:

OKRA Technologies is a leading European artificial intelligence (AI) company for life sciences. Our goal is to empower life science executives at their desks or whilst on the move, with explainable AI outputs. OKRA’s solutions deliver suggestions, predictions and explanations to enable life sciences executives and operational teams to drive the right drug to the right patient with humanised and understandable AI outputs. The OKRA engine learns from real-world data, structured, unstructured, clinical, commercial and scientific literature to drive the right insight to the different teams in life sciences. Our deep expertise in AI, combined with in-depth medical and product knowledge from life science leaders, has allowed us to develop and co-create products that can transform the way life sciences approach traditional industry challenges. We focus on operationalising AI in an ethical way by placing users of these systems at the centre.

[Interview] The Rise of Quantum Physics in Drug Discovery

   by Andrii Buvailo    1225
[Interview] The Rise of Quantum Physics in Drug Discovery

Computer-aided drug design (CADD) is a central part of so-called “rational drug design”, pioneered in the last century by companies like Vertex. Over the last decades, CADD had great influence on the way new therapeutics are discovered, however, it also showed limitations due to modest accuracy of computational tools.  

The majority of software tools used for computational chemistry and biology rely on molecular mechanics -- a simplified representation of molecules, essentially reducing them down to “balls and sticks”: atoms and bonds between them. In this way it is easier to compute, but accuracy suffers greatly.

In order to gain adequate accuracy, one has to account for the electronic behavior of atoms and molecules, i.e. consider subatomic particles -- electrons and protons. This is what quantum mechanical (QM) methods are all about -- and the theory is not new, dating back to the early decades of the 20th century.  

[Interview] Adoption of AI-driven Tools By The Life Sciences Professionals: What Is Coming In 2018?

   by Andrii Buvailo    2626
[Interview] Adoption of AI-driven Tools By The Life Sciences Professionals: What Is Coming In 2018?

The previous year was rich in discussions and events one way or another related to potential applications of artificial intelligence (AI) advances for the benefit of drug discovery and development.

(Note: For the sake of simplicity, the term “AI” will be applied herein interchangeably with terms like “machine learning” (ML), “deep learning” (DL), “neural networks” (NN) etc., although conceptually, those terms are quite different in meaning. The term AI describes a field of computer science studying how to make a computer intelligent at doing something, while terms like ”machine learning”, “deep learning”, and “neural networks” relate to algorithms and methods by which it can be achieved.).

[Interview] The Current Status Of AI In Drug Discovery And Looking Forward Into 2018

   by Andrii Buvailo    4893
[Interview] The Current Status Of AI In Drug Discovery And Looking Forward Into 2018

Without a doubt, the area of artificial intelligence (AI) has been a sensation lately -- judging by the amount of hype around this topic. But the hype is not a guarantee of a real breakthrough, which is defined by facts and measurable achievements, not just loud statements.

The fact is, however, AI-driven systems managed to learn chess at a champion level in just 4 hours, and beat human champions in Jeopardy, and Go -- we all know that. And Facebook can recognize faces in a blurry photo where you are hanging out with a bunch of friends -- not worse than you (human) can do. You can try and see it for yourself anytime -- it works!