BPT Crunch

Companies on the Cutting Edge of Healthcare Innovations

back to Marketplace

Lycia Therapeutics

Lycia Therapeutics logo



Protein Degraders Startups

Developing first-in-class therapeutics that degrade extracellular proteins to address difficult-to-treat diseases. Company building upon the novel platform developed by academic founder Professor Carolyn Bertozzi at Stanford University to develop LYTAC (lysosomal targeting chimera) protein degraders that harness the cell’s lysosomal trafficking and degradation pathway to target both soluble and membrane-bound extracellular proteins. Applications of the LYTAC platform include: targeting challenging membrane proteins, clearing pathogenic immune complexes in circulation and depleting antibodies to specific antigens of interest. The platform can potentially deliver next-generation therapeutics to address a range of difficult-to-treat diseases, including cancer and autoimmune diseases.

Lysosomal Targeting Chimera (LYTAC)

Posts Mentioning This Company

Protein Degraders Take Industry By Storm

Proteins are essential components of living matter — they function as building blocks for cells and tissues, as well as participate in signaling and practically all biochemical activities.  However, each protein operates correctly only for a limited time and is eliminated by molecular machinery after it has reached its “functional …