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Glen Research

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Antisense Oligonucleotides

Glen Research Corp. provides reagents and services for DNA research. It offers a range of phosphoramidites and supports for the chemical synthesis, modification, labeling, and purification of DNA and RNA oligonucleotides. The company also offers modifiers and reagents for labelling oligonucleotides during the synthesis. In addition, it provides RNA monomers and 2'-OMe-RNA monomers for use in antisense therapeutic and probe experiments, ribozyme studies, and other physical studies.

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Antisense Oligonucleotides Make Sense

Antisense oligonucleotides (ASOs) are short (about 12 to 25 nucleotides long), synthetic single strands of DNA or RNA that are complementary to a chosen sequence. They can alter RNA and reduce, restore, or modify protein expression. ASOs interact with proteins on the surface of cells and enter the cytoplasm. Then …