Our proprietary platform leverages Second Harmonic Generation (SHG) to measure structural changes of biomolecules in real time and with high throughput. Biomolecules undergo conformational changes that regulate activity and impact how they interact with other molecules in a pathway. By combining knowledge about a drug target’s native and disease-relevant biology with our platform, we can efficiently discover and develop molecules that induce functionally relevant structural changes in difficult-to-drug targets. Therefore, our drugs treat disease by inducing the desired conformational state in a key target.