Neuroscience Drug Development Europe 2023

This in-depth event will detail the journey of neuroscience discovery from initial lead through to clinical trials, bringing together leading companies for discussion, knowledge-sharing and focused networking

Track 1: Therapeutic Strategies, Enabling Technologies & Biomarker Development 

• Advancements and emerging trends in the application of technology in developing neurological treatments
• Neuroscience biomarker development
• Translational approaches for drug discovery
• Opportunities and challenges of designing and implementing targeted diagnostics and therapeutics
• Diagnostic tool development
• Digital Pathology, AI and Imaging strategies for Biomarker development

 
Track 2: Drug Discovery for Neurodegenerative Diseases 

• Target identification and validation approaches
• Stem cell technology to fuel drug discovery
• iPS cells for disease modelling and drug discovery
• Blood brain barrier in CNS drug discovery
• Assay Development & Screening
• In vitro and in vivo disease modelling
• The role of informatics in CNS drug discovery

This event is co-located with the Discovery Europe 2023

Attendees will have full access to both events.

Discovery Europe 2023

Join and network with over 400 industry leaders at Discovery Europe: In-Person, where we will address the latest advancements in target identification, validation and HIT optimisation.

The 2-day programme addresses drug discovery in new modalities such as protein degradation, and case studies on the integration of screening approaches in phenotypic and genomics-based discovery, Organ-on-a-chip and 3D modelling.

Learn about key focus areas in drug design including AI in drug design: in chemical synthesis, target ID capabilities & lead identification/optimisation.

Join our 2-day innovation showcase situated alongside the main programme, which aims to inspire growth and create collaboration opportunities for all who attend.

Spatial Biology US 2023

Join 300+ leaders, experts and researchers at the Spatial Biology US:
In-Person, connecting global academic & research organisations as well as pharma representatives for high-level discussions on the latest innovations in spatial research & technologies.

This 2-day event is designed specifically for the US market, we are bringing together spatial experts, researchers and scientists for participating in focused discussions, workshops and give presentations that mirror the current challenges and future opportunities of the spatial biology market.

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This Year's Agenda at a Glance

Day One

Track 1: Emerging Technologies Techniques and Approaches

• Overview of different spatial omics technologies 
• Transcriptomics, metabolomics, proteomics, spatial genomics – approaches and techniques
• Advanced technologies: pathology and spatial transcriptomics 
• Combining different multi-modal technologies

Track 2: Moving Spatial Biology Towards The Clinic

• How can spatial biology change diagnostics practices  
• Accelerating adoption of spatial technologies by pathologists 
• Spatial approaches to personalized medicine
• Challenges in the adoption of translational drug research
• The use of spatial biology in:
     » DMPK
     » ADME
     » R&D 

• Biomarkers, companion diagnostics – drug development applications

Track 3: Bioinformatics & Data Analysis

• Overcoming the challenges in spatial data analysis 
• Advanced computational tools 
• Data integration & visualization
• Multi-modal data analysis
• Spatial transcriptomic datasets
• Data access – how we can make the data accessing for more users? 
• Data standardization, integration & quality control methods

Day Two

Track 1: AI-Powered Imaging & Digital Pathology For Spatial Biology

• Adoption and utilization of AI/ML for spatial analyses  
• Label free imaging technologies – imaging mass spec 
• Accelerating the discovery of novel biomarkers and drug targets using spatial imaging
• Tissue imaging and analysis using advanced spatial profiling techniques

Track 2: Use Cases From Spatial Omics

Spatial proteomics 

• Spatial transcriptomics
• Spatial metabolomics 
• Spatial genomics:
     » Complementary role of dissociated single-cell/nucleus omics approaches in spatial biology 

• Case studies from disease areas:
     » Oncology
     » Neuroscience 
     » Lung diseases 

RNA Therapeutics & Delivery US 2023

Gain invaluable insights into the latest formulation, design & delivery of RNA therapeutics. Key opinion leaders will be addressing novel mRNA structures, therapeutic case studies and advanced delivery strategies for RNA.

Across four in-depth sessions the latest improvements pushing the industry forward will be addressed: from stability & clinical manufacturing, RNA computational design approaches, through to case studies & recent developments in RNA delivery platforms. Stay at the forefront of the growing interest in this area and hear case studies from the applications of RNAs in therapeutics and delivery challenges & future opportunities.

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Agenda at a Glance

Day One

RNA Formulation & CMC

• Nanoparticles/liposomes/exosomes-based formulations 
• Overcoming challenges in mRNA and particle characterization 
• Analytical & purification methods
• Stability & clinical manufacturing (CMC)
• mRNA vaccine formulation development 

NextGen RNA Design, Structures & Novel Technologies

• AI/ML & computational-assisted design approaches for siRNA and mRNA 
• Designing RNA:
  • Structural characterisation
  • Formulation design for optimal delivery
  • Software tools & design practices
• Novel technologies:  
  • Circular RNA 
  • Advances in mRNA technology 

Day Two 

Recent Advances in siRNA, mRNA & Antisense Drug Delivery

• Latest developments in delivery modalities:
  • Viral
  • Non-viral  
• Tissue & cell targeting 
• Novel modes & platforms for delivery 
• Developing RNA technologies 
• Alternative delivery approaches:
  • Oral delivery of oligos  

Application Areas of RNA Therapeutics

• Therapeutic case studies:
  • Cardiovascular diseases
  • Oncology 
  • Infectious & viral diseases 
  • Neurodegenerative diseases 
  • Pulmonary diseases 
  • Genetic disorders & medicines 

Gene Therapy Development & Manufacturing 2023

Join over 250 scientific leaders engaging in scientific discussions on the latest strategies and technologies to accelerate gene therapy production.

Benefits to attending include…

Connect with over 250 attendees representing global pharmaceutical organizations, leading biotech companies and internationally renowned academic institutions. 

Gain insights into the innovative technologies in gene editing, including CRISPR, ZFNs and TALENS and the translation of these technologies to clinical research 

Featuring key case studies on advanced analytical strategies for gene therapy and vector development, to support the successful commercialisation of therapeutic products 

Maximise your experience with our fully featured Event App, with selected presentations available to watch on-demand and extensive networking features

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Antibody Engineering 2023: Online

An intensive 2-day meeting that delves into the latest in antibody engineering and antibody-based therapeutics & a meeting place for experts working within engineering, computational tools and antibody-based therapeutics.

Benefits to Attending

Hear from and meet with the leading figures in the antibody, ADC and bispecifics engineering antibody-based therapeutics; offering in-depth presentations and new inspiring ideas to advance your research

Engage in in-depth panel discussions, roundtables and workshops brining together like-minded experts to address the pressing challenges & opportunities of the market

Explore case studies including antibody gene therapy and developing antibody therapies aiding the treatment of Covid-19

Agenda at a Glance

Day One

AI/ML & Emerging Technologies in Antibody-based Molecular Engineering

• In silico engineering of antibodies 
• Engineering antibody-based therapeutics with improved drug-like properties 

• Designing and engineering of new and required antibodies 
• AI/ML in antibody engineering 
• In vivo antibody expression  
• Alternative modalities & antibody fragments 

Day Two

Towards Optimising Antibody-Based Therapeutics and Modes of Action

• New strategies & methods in handling novel & difficult targets 
• Transforming targets for antibody-based therapeutics 
• Assessing target specificity
• Fc engineering