Reporting First Direct Sequence of SARS-CoV-2 RNA
The Lachlan Coin and Sebastian Duchene teams and collaborators in the Department of Microbiology and Immunology, University of Melbourne, Australia, …
Biopharma Insights
Synonymous Mutations Can Affect Protein Folding And Impair Cellular Fitness
Synonymous codon substitutions affect the mRNA coding sequence, but the encoded amino acid sequence remains unchanged. Therefore, ostensibly these substitutions …
COVID-19 Forcing You To Go Digital? You’re Missing A Trick
Moments of crisis always mean change. In these times, it’s tempting to reach for quotes from leaders who successfully navigated through turbulent …
Coronavirus - My Secret Hope
Coronaviruses are a large family of viruses that cause disease in animals and humans. They were discovered as a cause …
New Study Shows Remdesivir Prevents Coronavirus MERS-CoV Infection In Monkeys
In a new study, researchers from the National Institutes of Health reported that the experimental antiviral drug remdesivir (also known as …
How Pharma Reacts To Wuhan Coronavirus Outbreak
UPDATE April 04. 2020. The number of confirmed cases of COVID19 approaches 1M globally. Since too many drug repurposing programs …
Structural Basis of Poxvirus Transcription Revealed
In order for viruses to proliferate, they usually need to be supported by infected cells. In many cases, the molecules …
The Evolution Of Pharmaceutical R&D Model
There is a plethora of analytics reports, including ones by Deloitte, DKV Global, and Ernst and Young, all pointing out …
Next-Generation Sequencing Is The Next Big Thing In Pharmacogenomics
Pharmacogenomics seeks to understand underlying genetic markers that influence treatment responses and modification of therapies to increase efficacy treatment success …
Hunting Dark Genes For Druggable Targets
About one in three human proteins is understudied. Even when quantifying data is available from multiple sources, "dark" genes and proteins …
Pharma Companies Join Forces to Train AI for Drug Discovery Using Blockchain
The newly organized research project “MELLODDY” (Machine Learning Ledger Orchestration for Drug Discovery), involving ten large pharma companies and seven …
"Hot" Research Areas in Drug Discovery - 2019
Things like gene editing, stem cells, immunotherapies and new types of biologics are now mega-trends in the pharmaceutical industry, widely …