Latest Insights - page 89 | BiopharmaTrend

How Latest Drug Candidates Were Discovered? (Retrospective Review, 2016-2017)

Recently D.G.Brown and J.Boström of AstraZeneca published an insightful analysis, where they reviewed lead generation research strategies behind 66 small molecule clinical candidates published over 2016-2017 in Journal of Medicinal …

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Top 7 Trends In Pharmaceutical Research In 2018

Being under ever-increasing pressure to compete in a challenging economic and technological environment, pharmaceutical and biotech companies must continually innovate in their R&D programmes to stay ahead of the game. …

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2018 Brings A Surge Of Activity In The “AI For Drug Discovery” Space

(Last updated: 15.03.2018) The idea of using artificial intelligence (AI) to accelerate drug discovery process and boost a success rate of pharmaceutical research programs has inspired a notable amount of …

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[White paper] High Throughput Quantum Chemistry for Drug Discovery - Towards Reaction Screening

In the domain of drug discovery, there can be a world of difference between a computer-generated hit compound, which is predicted to bind well to a drug target and what …

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[Interview] Adoption of AI-driven Tools By The Life Sciences Professionals: What Is Coming In 2018?

The previous year was rich in discussions and events one way or another related to potential applications of artificial intelligence (AI) advances for the benefit of drug discovery and development. …

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A Clear Example of AI Value For Drug Discovery Has Arrived

With all the hot discussions (for instance, here, here, here and here) going on right now among medicinal chemists, pharmaceutical researchers, and data scientists as to what artificial intelligence (AI) …

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A Brief Guide To Assay Technology For Efficient Drug Discovery -- Part 1

Effective drug discovery begins with the right assay, but the definition of "right" will shift as technology advances. More often than not, "right" is the product of tribal knowledge, namely …

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[Interview] The Current Status Of AI In Drug Discovery And Looking Forward Into 2018

Without a doubt, the area of artificial intelligence (AI) has been a sensation lately -- judging by the amount of hype around this topic. But the hype is not a …

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Three Insights For Immuno-oncology Drug Discovery

Immunotherapies are hot property. Immuno-oncology is the crown jewel. But the road to riches, and more importantly cancer cures, is now crowded and full of potholes. Drug hunters need to …

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The Homunculus Metaphor Revisited In Drug Discovery: Body-on-a-Chip

The16th century alchemical and 19th century science fiction revival of a miniature human being in a test tube is undergoing a radical upgrade. Microfluidics, complex organoid cultures, and nanodetection of …

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36 Web Resources For Target Hunting In Drug Discovery

Choosing the right biological target or a combination of targets is a fundamental task for any successful drug discovery project. All the subsequent efforts -- be it a small molecule …

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How Many Drug Targets Are There? A Status Update Review

The question is often raised, but the answer remains to be uncovered because the definition of drug "target" continues to evolve. Historical conceptualization is focused on catalytic sites, substrate binding …

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