BioPharmaTrend
Latest News
All Topics
  • Artificial Intelligence
  • NeuroTech
  • Premium Content
  • Knowledge Center
Interviews
Companies
  • Company Directory
  • Sponsored Case Studies
  • Create Company Profile
More
  • About Us
  • Our Team
  • Advisory Board
  • Citations and Press Coverage
  • Partner Events Calendar
  • Advertise with Us
  • Write for Us
Subscribe
Login/Join

This Discovery Of Immune Cells May Start The Development Of New Anti-cancer Therapies

by Caroline Green  (contributor )   •   Feb. 25, 2020  

Disclaimer: All opinions expressed by Contributors are their own and do not represent those of their employers, or BiopharmaTrend.com.
Contributors are fully responsible for assuring they own any required copyright for any content they submit to BiopharmaTrend.com. This website and its owners shall not be liable for neither information and content submitted for publication by Contributors, nor its accuracy.

   Biopharma insight   
Share:   Share in LinkedIn  Share in Bluesky  Share in Reddit  Share in Hacker News  Share in X  Share in Facebook  Send by email   |  

Recently, in research published in the Immunity, researchers from University College London in the United Kingdom revealed that a special type of immune cells can be activated to kill cancerous cells through research on mice. Related research may give hope for the development of new types of anticancer therapy.

#advertisement
How BenchSci’s ASCEND Builds a Map for Biomedical Reasoning

Researcher Sergio Quezada said that after immunotherapy, some immune cells that have traditionally been considered to assist or regulate, such as some CD4 + T cells, become toxic and can directly kill cancer cells. Now researchers have revealed the molecular and cellular mechanisms behind its activity; researchers have found that T cell growth factor IL-2 and transcription factor Blimp-1 are mainly responsible for turning on the potential killing activity of CD4 + T cells in cancerous tumors.

Researchers point out that these immune cells have amazing potential for killing cancer cells, but to maximize their potency, we need to know how the mechanism is activated; this study provides evidence and reasons to use Blimp- 1 to maximize the anti-tumor activity of CD4 + T cells; researchers are currently researching to develop new personalized cell therapies that increase Blimp-1 activity to drive potential tumor control. T cells are a special class of lymphocytes that play a key role in the body's immune response. In immunotherapy, T cells can be modified to protect against cancer, and these cells can "patrol" the body and find infected cells to kill it; however, T cells do not recognize most cancers because cancers originate from the body's own tissues and appear normal for most T cells, which may pose a great challenge to T cell therapy, so researchers need to find new ways to drive T cells to directly kill cancer cells.

Researcher Professor Karl Peggs said that cell therapies have only recently entered the clinic and become mainstream. There are still many unknowns on how to optimize these therapies, especially how to improve their therapeutic activity in solid tumor cancers; the results of this paper can help researchers gain insight into the regulators of T cell differentiation, thus providing corresponding novel elements to help target and enhance the efficacy of therapies. Such studies can also help scientists understand the intricacies of the body's immune system and how it can be used to effectively kill cancer cells.

Share:   Share in LinkedIn  Share in Bluesky  Share in Reddit  Share in Hacker News  Share in X  Share in Facebook  Send by email

You may also be interested to read:

The Key Role Of Stem Cells In Lethal Gastric Cancer Revealed
by Caroline Green

 

#advertisement
ThermoFisher Scientific: Integrated genetic technologies for cell therapy development
#advertisement
Webinar: AI in Clinical Trials

BiopharmaTrend.com

Where Tech Meets Bio
mail  Newsletter
in  LinkedIn
x  X
gnews  Google News
rss  RSS Feed

About


  • What we do
  • Citations and Press Coverage
  • Terms of Use
  • Privacy Policy
  • Disclaimer

We Offer


  • Premium Content
  • BioTech Scout
  • Interviews
  • Partner Events
  • Case Studies

Opportunities


  • Membership
  • Advertise
  • Submit Company
  • Write for Us
  • Contact Us

© BPT Analytics LTD 2025
We use cookies to personalise content and to analyse our traffic. You consent to our cookies if you continue to use our website. Read more details in our cookies policy.