Turn Biotechnologies

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Turn Biotechnologies

Turn Biotechnologies logo

Website
http://www.turn.bio

Founded
2018

Patents
5

Technologies

Aging Research

Turn Bio’s goal is to address multiple aging-related indications using a single powerful reprogramming therapy that turns old cells young again, aiding in the rejuvenation of an aged human body. Company focused on restoring cells’ youthful vigor to repair damage caused by the aging process.

aging research cell reprogramming

Posts Mentioning This Company

14 Cutting-Edge Startups Focusing On RNA Research

For many years, the focus of therapeutic developments and scientific research was directed at the genome and proteins. Yet, there is a completely different level of cell regulation: the transcriptome level, presented by ribonucleic acids (RNAs).

R&D Platform

ERA™ and iPSC represent two ends of the cellular reprogramming continuum. Both technologies use carefully formulated mRNA cocktails of transcription factors – specific proteins like Myc, Oct3/4, Sox2 and Klf4 – that turn a gene on or off by controlling the rate of transcription of genetic information from DNA to messenger RNA. This information controls the cell’s function.

With ERA™, a cell’s exposure to both the dosing and timing of transcription factors is carefully controlled and more limited than with iPSC. The goal is to maintain cellular identity, but restore cell effectiveness by “turning back the clock” on the epigenome, which regulates how a cell functions and records cellular age.