A Landscape of Artificial Intelligence (AI) In Pharmaceutical R&D

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COVID-19

Section: Biopharma Insights     View all sections


[Interview] A Company on the Cutting Edge of COVID-19 Vaccine Development

   by Andrii Buvailo    995
[Interview] A Company on the Cutting Edge of COVID-19 Vaccine Development

Recently, COVAXX announced it would soon enter human trials as the company is focused on rapidly developing a Multitope Peptide-based Vaccine (MPV) against SARS-CoV-2. While the biotech industry is now on a race to develop vaccines to curb COVID-19 pandemics, with several dozen players competing for the future market, COVAXX is a special case that can not be taken lightly.

Not only COVAXX’s new vaccine candidate is constructed off a commercially proven peptide-based vaccine platform by United Biomedical (UBI), a leader with a 30-year history in creating vaccines with over 500 million doses sold annually and 5 billion -- cumulatively in animal health indications for infectious disease that has demonstrated safety and efficacy. But it is also co-founded by two biotech “stars” of modern-day: Peter H. Diamandis, M.D., founder and executive chairman of XPRIZE, executive founder of Singularity University, and a dozen other tech companies, a popular science author; and Mei Mei Hu, co-founder of United Neuroscience, a member of Fortune “40 Under 40” and TIME “100 Next List”.

A Leader in COVID-19 Vaccine Race, and the Bright Future for mRNA

   by Ivan Kondratov    617
A Leader in COVID-19 Vaccine Race, and the Bright Future for mRNA

Recently my favorite website ENDPOINTSNEWS published a rating of key players in the ongoing COVID-19 vaccine race. Compared to many vaccine developers with announced initiatives in this space, all the 28 organizations in the ENDPOINTSNEWS list stated at least preliminary positive results of their vaccine programs, and are firmly advancing them towards later stages of development. 

By the way, a notorious “Russian vaccine” by The Gamaleya Research Institute of Epidemiology and Microbiology also made its way to this list under the number 6, but I prefer not to touch upon this development. A lot has been said already about this story - to the point, and not so much. 

In this post I would rather talk about the number one in the list, a development undeservedly underrated by the media, which however might be the first to actually enter the global SARS-CoV2 vaccine market…

How To Be Ready For Future Pandemics?

   by Andrii Buvailo    813
How To Be Ready For Future Pandemics?

What do antibiotic-resistant bacteria (“superbugs”) and coronaviruses have in common? They both can kill lots of people globally, and they both have been commercially unattractive targets for the pharma business for too long.

 

[Interview] How COVID-19 Catalyzed AI-assisted Open Science Drug Discovery

   by Andrii Buvailo    1338
[Interview] How COVID-19 Catalyzed AI-assisted Open Science Drug Discovery

Biopharma companies are now racing to find much-needed cures against SARS-CoV-2, a virus that caused the largest global pandemic of our time. One notable effort is the COVID Moonshot project, organized by an international consortium of scientists from academia, biotechs, contract research organizations (CROs), and pharma -- all working pro bono or via crowdfunding, philanthropy, and grants. 

The aim of the project is to rapidly develop easily manufacturable antiviral drugs that can inhibit the SARS-CoV-2 main protease, which is believed to be an Achilles heel of the coronavirus. The project is managed by PostEra, a startup company that uses artificial intelligence (AI) algorithms to map routes for chemical synthesis to speed the drug-discovery process.